TY  - JOUR
T1  - Effects of <I>Convolvulus arvensis</I> (Binweed) on the Activity of Drug Metabolizing Enzymes in Liver of Rats
AU - , M.E. Al-Bowait AU - , S.E.M. Barakat AU - , M.H. Al-Nazawi AU - , M.E. Barri AU - , A.M. Homeida 
JO  - Journal of Animal and Veterinary Advances
VL  - 5
IS  - 9
SP  - 729
EP  - 731
PY  - 2006
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2006.729.731
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2006.729.731
KW  - Convulvulus arvensis
KW  -liver
KW  -drug metabolizing enzymes
KW  -rats
AB  - The effects of feeding <I>convulvulus arvensis</I> (binweed) at 0.5 and 1g/rat were investigated. Binweed produced no clinical effects or gross lesions in rats. The plant caused decreased concentration of protein in liver homogenate and inhibited the activity of phase-1 but not phase-2 drug metabolizing enzymes. In view of binweed modulating effects on drug metabolizing enzymes, consumption of binweed by human and animal should be prohibited.
ER  -