TY  - JOUR
T1  - The Anthelmintic Activity of Selected Indigenous Medicinal Plants Used by The anyankole of Western Uganda
AU - , Tuwangye Innocent AU - , Olila Deogracious 
JO  - Journal of Animal and Veterinary Advances
VL  - 5
IS  - 8
SP  - 712
EP  - 717
PY  - 2006
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2006.712.717
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2006.712.717
KW  - Ascaricidal
KW  -Vernonia amygdalina
KW  -Cassia didymobotrya
KW  -Rhoicissus tridentata
KW  -Phytolacca dodecandra
KW  -Euphorbia hirta
KW  -Aspillia Africana
KW  -Cymbopogon nardus
AB  - Recently, there has been growing interest in the traditional cures of livestock diseases. This is because industrially produced drugs are too expensive for some sectors of the farming community especially in the developing world.  Medicinal plants are often cheaper and more easily available than the commercially produced drugs. The self-help study in form of traditional medicines (especially from medicinal plants), offer a way out by making use of resources available within the communities themselves. Despite the steady increase in demand for herbal medicines over the past decade worldwide, a great majority of herbal products are not pharmacologically assessed for their quality, safety and efficacy, nor are they licensed as medicine. In this study some of the medicinal plants used by the Banyankole (an ethnic group with a long history of cattle-keeping and the use of medicinal plants) have been tested <I>in vitro</I> using the Ascaris  model.   Seven  plants were     studied     (<I>Vernonia     amygdalina</I>, <I>   Cassia      didymobotrya</I>, <I>     Rhoicissus    tridentata</I>, <I>  Phytolacca dodecandra</I>, <I>Euphorbia hirta</I>, <I>Aspilla africana</I> and <I>Cymbopogon nardus</I>). <I>Aspillia</I> <I>africana</I> and <I>Cymbopogon nardus</I> did not show anthelmintic activity in this test system. The other five showed anthelmintic activity (<I>Vernonia amygdalina</I>, <I>Cassia didymobotrya</I>, <I>Rhoicissus tridentata, Phytolacca dodecandra</I> and <I>Euphorbia hirta</I>). Extracts of <I>Vernonia amygdalina</I>, <I>Rhoicissus tridentata</I> and <I>Cassia</I> <I>didymobotrya</I> showed higher  activity  than <I> Euphorbia  hirta</I>  and <I> Phytolacca  dodecandra  (Vernonia  amygdalina</I>  (ED<SUB>50</SUB>)  of   3.533 mg  mL <SUP>1</SUP>,<I>  Rhoicissus  tridentata</I>  (ED<SUB>50</SUB>)  of  4.355  mg  mL <SUP>1</SUP><I> </I> and <I>  Cassia</I> <I> didymobotrya</I>  (ED<SUB>50</SUB>)  of    4.880  mg mL <SUP>1</SUP>; Euphorbia<I> hirta</I> (ED<SUB>50</SUB>) of 5.866 mg mL <SUP>1</SUP> and <I>Phytolacca dodecandra</I> (ED<SUB>50</SUB>) of 7.151 mg mL <SUP>1</SUP>). Further studies on the five plants are needed. Phytochemical analysis to determine the active principles that are responsible for anthelmintic activity are urgently called for. This would help in identifying the spectrum of activity of the extracts as well as determining their mechanism of action. Studies should also be carried out on these plants to determine their toxicity and also their effect on other helminthes apart from Ascaris.
ER  -