TY  - JOUR
T1  - <I>In vitro</I> Ovicidal and Larvicidal Activity of the Leaf, Bark and Root Extracts of <I>Peltophorum africanum</I>  Sond. (Fabaceae) on <I>Haemonchus contortus</I>
AU - , E.S. Bizimenyera AU - , J.B. Githiori AU - , G.E. Swan AU - , J.N. Eloff 
JO  - Journal of Animal and Veterinary Advances
VL  - 5
IS  - 8
SP  - 608
EP  - 614
PY  - 2006
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2006.608.614
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2006.608.614
KW  - Ovicidal
KW  -larvicidal
KW  -extracts
KW  -Haemonchus contortus
KW  -Peltophorum africanum
AB  - The <I>In vitro</I> efficacy of the extracts of <I>Peltophorum africanum </I>Sond. (Fabaceae<I>), </I>was determined against <I>Haemonchus contortus</I>. Acetone extracts of the leaf, bark and root, at concentrations of 0.008 to 25 mg mL <SUP>1</SUP> were incubated at 23<SUP>o</SUP>C with the eggs and larval stage (L<SUB>1</SUB>) of the parasite for two and five days,  respectively. Thiabendazole and water were positive and negative controls, respectively. Increasing the concentration of extracts caused a significant (p&lt;0.05) increase in inhibition of egg hatching, and larval development. At concentrations of 0.2 and 1.0 mg mL <SUP>1</SUP> the extracts inhibited egg hatching and development of L<SUB>1</SUB> to the infective stage (L<SUB>3</SUB>). No eggs and larvae (L<SUB>1</SUB>) of <I>H. contortus</I> were detected at concentrations of 5 and 25 mg mL <SUP>1</SUP>. The<I> in vitro</I> model may provide support of the traditional use of <I>P. africanum</I> extracts against helminthosis. Suitable methods of plant extraction, adaptable to rural use may help rural communities control helminthosis.
ER  -