TY  - JOUR
T1  - Determination of Susceptibility of Malaysian <I>Leptospira </I>Isolate to Antimicrobial Agents
AU - , Khairani-Bejo AU - , A.H. Norhamizah AU - , A.R. Bahaman AU - , A.A. Kadir 
JO  - Journal of Animal and Veterinary Advances
VL  - 5
IS  - 2
SP  - 111
EP  - 113
PY  - 2006
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2006.111.113
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2006.111.113
KW  - Leptospira sp.
KW  -antibiotic
KW  -mortality
AB  - One <I>L. hardjo</I> Malaysian isolate and five <I>Leptospira sp. </I>reference strain<I> </I>namely<I> L. pomona, L .icterohaemorrhagae, L. canicola, L. australis </I>and<I> L. hardjo </I>Prajitno<I> </I>were selected in this study. The <I>Leptospira</I> strains were tested for it susceptibility against five types of antibiotics. The antibiotics are tetracycline, oxytetracycline, penicillin G, streptomycin and erythromycin. All the strains were observed under dark-field microscope for their  mortality after inoculation of 18 different concentration of antibiotic at 24, 48, 72, 96, 120, 144 and 168 h post inoculation. The study showed that tetracycline is the antibiotic of choice to treat leptospirosis because it is effective against most of the strains used in the study in very short time after inoculation. However, <I>L. canicola</I> was resistant against tetracycline but sensitive to penicillin G.
ER  -