@article{MAKHILLVR201811228046,
    title = {Study the Secondary Pathological Lesions},
    journal = {Veterinary Research},
    volume = {11},
    number = {2},
    pages = {14-19},
    year = {2018},
    issn = {1993-5412},
    doi = {vr.2018.14.19},
    url = {https://makhillpublications.co/view-article.php?issn=1993-5412&doi=vr.2018.14.19},
    author = {Khalil and},
    keywords = {LPS,pathological findings,Immunization,OMP,granulomatous lesion},
    abstract = {Snuffles disease is a major infectious disease
process in rabbits caused by Pasteurella multocida. The
importance of the Lipopolysaccharides (LPS) and Outer
Membrane Protein (OMP) in the immunization and
pathogenesis of the disease. This study aimed to identify
all the pathological findings in rabbits immunized with
LPS and OMP. For this reason a local strain of
Pasteurella multocida were used and their LPS and OMP
were extracted and purified and used for immunization of
rabbits. Following immunization and inoculation of a
challenge dose of the Pasteurella multocida, the bacterial
Isolation were mild to moderate at 4th, 8th day and mild
at 16th day post inoculation compared to heavy bacterial
isolates in the control non immunized group. Also, more
localized and granulomatous lesion were seen in
immunized groups compared to extensive and diffuse
septicemic lesions in non immunized control group.}
    }