@article{MAKHILLVR20082327927,
    title = {Effects of Crude Aqueous Extract of <I>Ocimum gratisssimum</I> Leaves on Testicular Histology and Spermiogram in the Male Albino Rat (<I>Wistar strain</I>)},
    journal = {Veterinary Research},
    volume = {2},
    number = {3},
    pages = {42-46},
    year = {2008},
    issn = {1993-5412},
    doi = {vr.2008.42.46},
    url = {https://makhillpublications.co/view-article.php?issn=1993-5412&doi=vr.2008.42.46},
    author = {Olufisayo O. and},
    keywords = {Aqueous extract,ocimum,testicular histology,spermiogram,reproduction,rat},
    abstract = {The effects of the aqueous leaf extract of <I>Ocimum gratisssimum</I> on testicular histology and spermiogram were investigated using 18 male albino rats. The rats were randomly divided into 3 groups: A-C, each containing 6 rats. Fifty grams of fresh leaves of <I>Ocimum gratisssimum</I> were rinsed, thoroughly blended in 100 mL of distilled water and filtered through filter paper. A 10x10<SUP>-4</SUP> and 5x10<SUP>-4</SUP> mL kg<SUP>-1</SUP> of the filtrate were administered to groups A and B, respectively thrice weekly for 5 weeks. Group C served as control and received distilled water. Histopathology revealed mild to severe congestion and edema as well as germinal tissue erosion of the seminiferous tubules. Spermatozoa motility, concentration, live-dead ratio and semen volume did not show significant changes (p&gt;0.05). However, differences in spermatozoa abnormalities between control and tested groups were highly significant (p&lt;0.01). Mean differences in sperm abnormalities between groups A (28.5), B (13.75) and the control were also greater than calculated Least Significant Difference (LSD) value of 2.146. These findings indicate antifertility properties of <I>Ocimum gratisssimum</I>.}
    }