@article{MAKHILLRJANS20082527617,
    title = {Blood Cellular and Biochemical Studies on Filariasis of Dogs},
    journal = {Research Journal of Animal Sciences},
    volume = {2},
    number = {5},
    pages = {128-134},
    year = {2008},
    issn = {1993-5269},
    doi = {rjnasci.2008.128.134},
    url = {https://makhillpublications.co/view-article.php?issn=1993-5269&doi=rjnasci.2008.128.134},
    author = {Mohamed A. Hashem and},
    keywords = {Filariasis,hematology,serum enzymes,creatinine,dogs},
    abstract = {The  present  research  was  done  on 82 stray dogs to be investigated for filariasis, hematological and serum chemistry profiles of naturally infested dogs. Out of the examined dogs, 14 (17.1%) were infested with <I> Dipetalonema  reconditum</I>,  12  (85.7%)  of them were males and 2 dogs (14.3%) were females. Microfilariae appeared as a snake like with a rapidly, forward movement across the microscopic field in wet smear while in Giemsa  stained smears showed a coiled or twisted appearance. Hematological studies revealed hemolytic anemia  (macrocytic  hypochromic  type) associated with low erythrocyte counts, hemoglobin concentration and hematocrit value. A marked increase  in  erythrocyte sedimentation rate, reticulocyte, thrombocyte, total and differential leucocytic counts were encountered, in comparison with the control group.  Biochemical analysis of sera from infested dogs showed a significant increase in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, serum bilirubin (total and indirect), total proteins, globulins, urea nitrogen, creatinine, inorganic phosphorus, potassium and a decrease in serum glucose, albumin, calcium and sodium values, with insignificant change in the magnesium level. It could be concluded that infestation of dogs with filariasis induced a hemolytic anemia, with disturbance in the liver and kidney functions.}
    }