@article{MAKHILLJFI20116221662,
    title = {Assessment of Dietary Bovine Lactoferrin in Enhancement of Immune Function and Disease Resistance in Common Carp (<I>Cyprinus carpio</I>)},
    journal = {Journal of Fisheries International},
    volume = {6},
    number = {2},
    pages = {41-45},
    year = {2011},
    issn = {1817-3381},
    doi = {jfish.2011.41.45},
    url = {https://makhillpublications.co/view-article.php?issn=1817-3381&doi=jfish.2011.41.45},
    author = {Mohammad,Farnaz,Saeed and},
    keywords = {Cyprinus carpio,A. hydrophilla,Lctoferrin,lymphocytes,supplementention,Iran},
    abstract = {Lctoferrin (LF) is an iron-binding glycoprotein plays an important role in the non-specific immune system in fish and mammals. Common carp (<I>Cyprinus carpio</I>) was fed bovine LF supplemented diets (0, 200, 400 and 600 mg kg<SUP>-1</SUP> diet) for 4 weeks. The effect of dietary LF on immune function and resistance to <I>Aeromonas hydrophilla</I> challenge was determined. The level of LF in diet had a significant force on survival following <I> A. hydrophilla</I> challenge with fish fed the 600 mg kg<SUP>-1</SUP> LF diet having significantly superior survival than control fish. There was increase in activity of non-specific and specific immune parameters (lymphocytes count, macrophage oxidative burst, serum lysozyme and bactericidal activities against <I>A. hydrophilla</I>) with addition of LF to diets. While there was not a corresponding increase in activity of total leukocytic count and neutrophil adhesion test. The increased resistance to <I>A. hydrophilla</I> with increasing dietary concentration of LF seemed to correspond with an enhancement of non-specific immune functions. In conclusion, dietary LF supplementation could be enhances the non-specific immunity and diseases resistance in common carp (<I>Cyprinus carpio</I>).}
    }