@article{MAKHILLJEAS2018131216337,
    title = {Indirect Response of Early Mouse Embryo to Oxidative Stress Evoked in Apoptosis Model},
    journal = {Journal of Engineering and Applied Sciences},
    volume = {13},
    number = {12},
    pages = {4300-4304},
    year = {2018},
    issn = {1816-949x},
    doi = {jeasci.2018.4300.4304},
    url = {https://makhillpublications.co/view-article.php?issn=1816-949x&doi=jeasci.2018.4300.4304},
    author = {O.A.,A.I.,V.M.,A.G.,M.A. and},
    keywords = {Oocyte and early embryo,NMRI mouse,apoptosis,hydrogen peroxide,electrochemically reduced,quantitative laser microtomography,cellular volume,Oocyte and early embryo,NMRI mouse,apoptosis,hydrogen peroxide,electrochemically reduced,quantitative laser microtomography,cellular volume},
    abstract = {Quantitative laser microtomography was employed to measure the single cell volume. NMRI mouse
zygotes and 2-cell embryos were shown to exhibit the shrinkage at apoptosis induced with ROS (40 min., H<sub>2</sub> O<sub>2</sub> , 
0.2 mM). Unlike early embryos, there was no influence of<i> in vitro</i> apoptotic circumstances on mature oocytes,
direct precursor of early embryogenesis. Dulbecco&#146;s solution prepared from electrochemically reduced
bi-distilled water allows the low redox potential in both normal and apoptotic conditions. The data obtained
permit us to suggest that ROS sub-milimolar concentrations likely act as the signaling impact. Cys-loo receptors
containing thiol group may be considered as the target of hydrogen peroxide molecules.}
    }