@article{MAKHILLJEAS2016111213960,
    title = {Biological Property of HDDMA Based Resin Matrix System for Dentistry},
    journal = {Journal of Engineering and Applied Sciences},
    volume = {11},
    number = {12},
    pages = {2673-2677},
    year = {2016},
    issn = {1816-949x},
    doi = {jeasci.2016.2673.2677},
    url = {https://makhillpublications.co/view-article.php?issn=1816-949x&doi=jeasci.2016.2673.2677},
    author = {Siti,Widowati and},
    keywords = {HDDMA,bis-GMA,cytotoxicity,cells,FRCs},
    abstract = {Recently, there is a great interest in the replacement of commercial bis-GMA resin matrix system for
dentistry. Bis-GMA is considered to be relatively cytotoxic and allergenic to human. A novel resin matrix
system based on HDDMA is under investigation. This study aimed to determine the biological property
especially the cytotoxicity property of proposed HDDMA-based resin matrix systems of FRCs material toward
fibroblast cells. Fifteen FRCs specimens were prepared and divided into 3 groups. Two groups were based on
HDDMA matrix systems and one group was bis-GMA-based. The cytotoxicity property was determined by
MTT method. The result revealed significant differences in cells viability between HDDMA-based matrices and
bis-GMA-based, whilst no significant difference between the two proposed HDDMA-based matrices. In
conclusion, proposed resin matrix systems based on HDDMA exhibited a less cytotoxic material than bis-GMAbased.}
    }