@article{MAKHILLIJTM20116219812,
    title = {Antioxidant Properties of Methanol Extract of Parquetina Nigrescens in Ulcerated Rats},
    journal = {International Journal of Tropical Medicine},
    volume = {6},
    number = {2},
    pages = {25-29},
    year = {2011},
    issn = {1816-3319},
    doi = {ijtmed.2011.25.29},
    url = {https://makhillpublications.co/view-article.php?issn=1816-3319&doi=ijtmed.2011.25.29},
    author = {O.R.,A.A.,F.S.,E.O.,O.O. and},
    keywords = {Parquetina nigrescens,SOD (Superoxide Dismutase),CAT (Catalase),ethanol,ulcer,Nigeria},
    abstract = {<I>Parquetina nigrescens</I> is a plant used in folk medicine in treating gastric ulcer. This study investigated the antioxidant properties of <I>P. nigrescens</I> in ethanol ulcerated rats. Rats were pretreated for 7 or 14 days with graded doses (500 and 1000 mg kg<SUP>-1</SUP>) of methanol extract of <I>P. nigrescens</I> before ulcer was induced on 8th or 15th day with absolute ethanol (1 mL/rat). The antioxidant properties of <I>P. nigrescens</I> were assessed using standard procedures. Intoxication with ethanol caused increased lipid peroxidation, reduced activities of Super Oxide Dismutase (SOD) and Catalase (CAT) and reduced protein concentration. Pretreatment with <I>P. nigrescens</I>, however, lowered lipid peroxidation, caused increases in activities of SOD, CAT and protein levels. This study therefore, shows that <I>P. nigrescens</I> possesses antioxidant properties that can protect against free radical induced ulcer.}
    }