@article{MAKHILLRJP20137412492,
    title = {Antidiarrheal Potentiality of Methanolic Extract of Different Parts of <I>Musa 
  sapientum</I> Fruits},
    journal = {Research Journal of Pharmacology},
    volume = {7},
    number = {4},
    pages = {41-47},
    year = {2013},
    issn = {1815-9362},
    doi = {rjpharm.2013.41.47},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9362&doi=rjpharm.2013.41.47},
    author = {Md.,S.M.,M.,Irfan and},
    keywords = {Musa sapientum,diarrhea,flavonoid,antibacterial,mice},
    abstract = {To investigate the antidiarrheal activities of the methanolic extract of peel (MSPL) and pulp (MSPP) of <I>Musa sapientum</I> fruits, the extract was studied for antidiarrheal property using castor oil and magnesium sulphate induced diarrheal model and charcoal induced gastrointestinal motility as well as PGE<SUB>2</SUB>-induced enterolooping test in mice. In addition, activities against some causative diarrheal pathogenic bacteria were also determined. At the doses of 100 and 200 mg kg<SUP>-1</SUP> body weight, both extracts significantly reduced the frequency and severity of diarrhea in test animals throughout the study period. Both extracts also showed a significant (p&lt;0.001, 0.05) reduction in the gastrointestinal motility in charcoal meal test, as well as PGE<SUB>2</SUB>-induced intrafluid accumulation. MSPL extract also displayed strong antibacterial effect against against <I>Staphylococcus aureus</I>, <I>Salmonella typhi</I>, <I>Shigella dysenteriae</I> and <I>Escherichia coli</I>. Altogether, these results suggest that the <I>Musa sapientum</I> fruit extracts could be used as a potential antidiarrheal agent.}
    }