@article{MAKHILLRJP20104212442,
    title = {Anti-Plasmodial and Larvicidal Effects of Surface Exudates of <I>Gardenia ternifolia</I> Aerial Parts},
    journal = {Research Journal of Pharmacology},
    volume = {4},
    number = {2},
    pages = {45-50},
    year = {2010},
    issn = {1815-9362},
    doi = {rjpharm.2010.45.50},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9362&doi=rjpharm.2010.45.50},
    author = {P.,J. and},
    keywords = {kaempferol-7-O-methylether,quercetin-4, 7-O-dimethylether,naringenin-7-O-methylether,surface exudates,Gardenia ternifolia,anti-plasmadial,LC50, IC50},
    abstract = {Various parts of <I>Gardenia ternifolia</I> (leaves, roots and stem bark) have been reported by traditional healers as a remedy against malaria fever. The aerial parts are coated with shiny materials rich in flavonoid aglycones. The crude acetone wash of the aerial parts showed anti-plasmodial activity of IC<SUB>50</SUB> values 1.06 and 0.94 &#956;g mL<SUP>-1</SUP> against chloroquine-resistant (W2) and chloroquine-sensitive (D6) strains of <I>Plasmodium falciparum</I>, respectively. Bioassay guided chromatographic separation of the crude extracts afforded five flavonoids; (naringenin-7-O-methylether, quercetin-4, 7-O-dimethylether, kaempferol-7-O-methylether, 4, 5-Dihydroxy-6, 7-dimethoxyflavanone, naringenin-4, 7-O-dimethyl-ether) and two steroids; (stigmasterol, &#946;-sitosterol). The same crude acetone surface extract as well as the pure isolates showed moderate larvicidal effects against 2nd instar <I>Ae. aegypti</I> larvae. Naringenin-7-O-methyl-ether was the most potent principle.}
    }