@article{MAKHILLRJP20082312419,
    title = {Antinociceptive and Anti-Inflammatory Effects of <I>Lonicera japonica</I> Thunb},
    journal = {Research Journal of Pharmacology},
    volume = {2},
    number = {3},
    pages = {38-42},
    year = {2008},
    issn = {1815-9362},
    doi = {rjpharm.2008.38.42},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9362&doi=rjpharm.2008.38.42},
    author = {M.R. Sulaiman,Z.A. Zakaria,S. Moin,M.N. Somchit and},
    keywords = {Lonicera japonica,flower’s buds,aqueous extract,antinociceptive activity,anti-inflammatory activity},
    abstract = {The present study was carried out to establish the antinociceptive and anti-inflammatory activities of the aqueous extract of <I>Lonicera japonica</I> flowers’ buds in various experimental animal models. The antinociceptive activity was measured using the abdominal constriction, hot plate and formalin tests, while, the anti-inflammatory  was   measured  using  the  carrageenan-induced  paw  edema. The dried flower’s buds of <I>L. japonica </I>was added with distilled water (1:10 w v <SUP>1</SUP>) and boiled for 2 h at 80°C. The supernatant collected was  freeze-dried   overnight   and   prior    to   use  was  diluted to the desired doses. The extract (30, 100 and 300 mg kg<SUP>-1</SUP>; administered intraperitoneally) exhibited significant (p&lt;0.05) antinociceptive and anti-inflammatory activities in all assays used. In conclusion, the flower’s buds of <I> L. japonica </I>possessed potential antinociceptive and anti-inflammatory activities that require further in-depth studies.}
    }