@article{MAKHILLRJP20071412407,
    title = {Effect of Aqueous Methanolic Stem Bark of <I>Maerua angolensis</I> (<I>Capparidaceae</I>) Extract on Blood Glucose Levels of Streptozocin-induced Diabetic Wistar Rats},
    journal = {Research Journal of Pharmacology},
    volume = {1},
    number = {4},
    pages = {75-78},
    year = {2007},
    issn = {1815-9362},
    doi = {rjpharm.2007.75.78},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9362&doi=rjpharm.2007.75.78},
    author = {A. Mohammed,Y. Tanko,M.A. Okasha,Y. Sadiq and},
    keywords = {Maerua angolensis,hypoglycemic activity,streptozocin,diabetes mellitus},
    abstract = {The hypoglycemic effect of aqueous methanolic extract of <I>Maerua angolensis </I>stem bark was investigated  in  streptozocin-induced  diabetic rats. A single  administration  of the extract at the doses of  250, 500 and 1000 mg kg <SUP>1</SUP>. There was a significant decreased in the blood glucose levels after 4 of extract administration  at  the  doses of  250  and  500  mg  kg <SUP>1</SUP>. Also after  8  and  24  h  of extract administration there was a significant decreased (p&lt;0.05) in the 3  dose administered. The  effective  dose  resides  at  the dose of 500 mg kg <SUP>1</SUP>. The Preliminary phytochemical screening revealed the presence glycosides, tannins, saponins, terpenes, flavonoids, carbohydrate, protein and alkaloids. The median Lethal Dose (LD<SUB>50</SUB>) in rats was calculated to be 3807.8 mg kg <SUP>1</SUP> body  weight.  In  conclusion  the  aqueous  methanolic  extract  of <I> Maerua  angolensis</I>  stem  bark possess anti-diabetic effect in streptozocin induced in diabetic rats.}
    }