@article{MAKHILLRJMS201711412176,
    title = {The Impact of using Botulinum Toxin-A on Urinary Tract
Infection in Patients with Overactive Bladder},
    journal = {Research Journal of Medical Sciences},
    volume = {11},
    number = {4},
    pages = {186-190},
    year = {2017},
    issn = {1815-9346},
    doi = {rjmsci.2017.186.190},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=rjmsci.2017.186.190},
    author = {Rola S.,Ameer K.,Rami S. and},
    keywords = {Overactive bladder,botulinum toxin-A,urinary tract infection,E. coli,prophylactic,antibiotic},
    abstract = {Botulinum toxin-A has been used in the treatment of overactive bladder effectively. The objective
of this study was to investigate the effects of using Botulinum Toxin-A (BoNT-A) in reducing the frequency
of urinary tract infections. The 119 patients were included in this study. A retrospective design was conducted
to collect data from patients who visited urology clinics at King Abdulla University Hospital. Results showed
that the mean age of study participants was 25.80+22.63 years, among them were 35(29.4%) males, 68.1% of
participants had at least one positive urine culture in the 6 months preceding the treatment. Among positive
cultures, E. coli was the most prevalent organism (42.6%) and the rate of mixed growth was about 30%.
Post-treatment urine cultures showed that about 44.5% were positive of which E. coli was the most prevalent
(37%). The rate of mixed growth had increased to about 39.22%. Taken together, our study showed that using
botulinum toxin-A is helpful in reducing urinary tract infection. Furthermore, botulinum toxin-A increased the
frequency of mixed growth and we might speculate that using a prophylactic antibiotic course accompanied
with its use is recommended.}
    }