@article{MAKHILLRJMS20159311942,
    title = {Warfarin Inhibits Tumor Metastasis Through an Immune-Modulatory, Coagulation-Independent Manner That Involves NK Cells: Possible Anti-Tumor Effects in Patients with OSCC?},
    journal = {Research Journal of Medical Sciences},
    volume = {9},
    number = {3},
    pages = {64-66},
    year = {2015},
    issn = {1815-9346},
    doi = {rjmsci.2015.64.66},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=rjmsci.2015.64.66},
    author = {Eva-Maria},
    keywords = {Warfarin,OSCC,immune-modulation,killer-cells,natural},
    abstract = {Tumor patients show alterations of the clotting mechanism by means of a hypercoagulable state. Warfarin’s anti-tumor action was reported in animal cancer models and in human studies with patients already receiving warfarin. An arrest of lung metastases was reported. The mechanism for this anti-tumor action seems to be coagulation-independent, probably involving immune-modulatory mechanisms related to NK function. It would be of great interest to evaluate the hypothesis that warfarin is able to modulate the generation of lymph-node metastases in OSCC by affecting NK receptors in an immune-modulatory manner.}
    }