@article{MAKHILLRJMS20159111923,
    title = {Molecular Characterization and Inhibition by Natural Agents of Multidrug Resistant Candida Strains Causing Vaginal Candidiasis},
    journal = {Research Journal of Medical Sciences},
    volume = {9},
    number = {1},
    pages = {1-7},
    year = {2015},
    issn = {1815-9346},
    doi = {rjmsci.2015.1.7},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=rjmsci.2015.1.7},
    author = {Gamal,Dina,Mahmoud,Ahmed and},
    keywords = {Genetic linkage,Candidiasis,Aqueous extract of alum and clove,Antifungal resistance,Candida spp.,Identification},
    abstract = {The prevalence percentage of vaginal candidiasis appeared to be 49% within Egyptian pregnant women suffering from vaginal pain and vaginal discharge. The 61.2% of the 49 patients were multigravidae and almost in the age range 20-30 years. Based on phenotypic and biochemical characteristics, the infective 49 isolates causing vaginal candidiasis could be classified and identified to C. <I>albicans</I> group (32 isolates), C. <I>tropicalis group</I> (12 isolates) and C. <I>dubliniensis</I> group (5 isolates). Three strains of them viz. C. <I>albicans</I> ZUH<SUB>1</SUB> , C. <I>trobicalis</I> ZUH<SUB>13</SUB> and C. <I>dubliniensis</I> ZUH<SUB>9</SUB> were resistant to 6 antifungal agents used and the antifungal resistance ability in each of them was genetically encoded and linked to one plasmid in each of them, almost in the range 600-800 bp. Of many natural agents used as antifungals, aqueous extracts of alum and clove inhibited vigorously the antifungal resistant strains: C. <I>albicans</I> ZUH<SUB>1</SUB> , C. <I>trobicalis</I> ZUH<SUB>13</SUB> and C. <I>dubliniensis</I> ZUH<SUB>9</SUB> ; no colony forming units were detected onto Sabouraud agar after 5 days of incubation from samples 9 treated with either alum or clove extracts.}
    }