@article{MAKHILLRJMS20126211833,
    title = {Management and Patient Selection for BRCA Genetic Testing to Identify Women at Increased Risk for Breast and Ovarian Cancers: A Review},
    journal = {Research Journal of Medical Sciences},
    volume = {6},
    number = {2},
    pages = {83-86},
    year = {2012},
    issn = {1815-9346},
    doi = {rjmsci.2012.83.86},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=rjmsci.2012.83.86},
    author = {Yakup and},
    keywords = {Brest cancer,BRCA gene mutation,surveillance,risk,women,Turkey},
    abstract = {Cancer caused by a mutated gene is a hereditary cancer rather than a sporadic cancer. Women who have inherited mutations in the <I>BRCA1</I> or <I>BRCA2</I> genes have substantially elevated risks of breast and ovarian cancer. Further genetic risk assessment is recommended for women who have &gt;20-25% chance of having an inherited predisposition to breast or ovarian cancer. Women with harmful mutations in either BRCA1 or BRCA2 have risk of breast cancer that is about 5 times the normal risk and a risk of ovarian cancer that is about 10-30 times normal. Mutation carriers have various options including extensive and regular surveillance, chemoprevention and risk-reducing surgery.}
    }