@article{MAKHILLRJMS20126311850,
    title = {<I>Cassia tora</I> L. Cream Inhibit Ultraviolet B Induced Oxidative Stress in Rats},
    journal = {Research Journal of Medical Sciences},
    volume = {6},
    number = {3},
    pages = {145-147},
    year = {2012},
    issn = {1815-9346},
    doi = {rjmsci.2012.145.147},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=rjmsci.2012.145.147},
    author = {Manmohan and},
    keywords = {O/W creams,Oxidative stress,glutathione,lipid peroxidation,antioxidant},
    abstract = {The aim of this study was to determine the <I>in vivo</I> antioxidant activity of newly formulated Oil in Water (O/W) creams of methanolic extract of <I>Cassia tora </I>L. leaves. O/W creams of methanolic extract of <I>Cassia tora </I>L. leaves was prepared, evaluated and tested for acute dermal toxicity study. The different O/W creams showed good physical characteristics and pass the sensitivity, irritation, grittiness and bleeding test. Exposure of Ultraviolet-B (UV-B) light decreased the reduced Glutathione (GSH), Catalase (CAT) and Superoxide Dismutase (SOD) activities and increased the Lipid Peroxidation (LPO). The oxidative stress induced by exposure of UV-B light in rats was minimized by single dose topical application of different concentrations of O/W creams and <I>Cassia tora</I> Methanolic extract (CTM). Researchers concluded that topical O/W creams and methanolic extract of <I>Cassia tora</I> leaves has potent antioxidant activity.}
    }