@article{MAKHILLRJMS202519531834,
    title = {Use of Cryo‐Anesthesia vs Topical Anesthetic Spray to Evaluate Pain Perception by Pediatric Patients During Greater Palatine Nerve Block: A Pilot Study},
    journal = {Research Journal of Medical Sciences},
    volume = {19},
    number = {5},
    pages = {1-5},
    year = {2025},
    issn = {1815-9346},
    doi = {makrjms.2025.5.1.5},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2025.5.1.5},
    author = {Shantanu,Amritjit,Swati,Haresh and},
    keywords = {Cryo‐anesthesia, greater palatine nerve block, topical anesthetic spray},
    abstract = {Effective pain management is crucial in pediatric dentistry, especially
during greater palatine nerve blocks (GPNB), which are often painful for
children. This study compared the effectiveness of topical anesthetic
spray and cryo‐anesthesia in reducing pain during GPNB in children using
a behavioral pain assessment scale. In this randomized, split‐mouth
clinical trial, children aged 7‐12 years requiring bilateral maxillary
posterior procedures received topical anesthetic spray at the first
appointment and cryo‐anesthesia at the contralateral site during the
second appointment. Intervention sequence was assigned via
computer‐generated randomization. Standardized GPNBs were
administered after pre‐injection interventions, and pain was assessed
using the Sound, Eye, and Motor (SEM) scale by a blinded examiner.
Comparisons were made using Wilcoxon signed‐rank tests.
Cryo‐anesthesia resulted in significantly lower SEM scores compared to
topical anesthetic spray (median total SEM: 7.0 vs. 10.0, p < 0.001), with
reductions observed in all scale components Cryo‐anesthesia is more
effective than topical anesthetic spray in minimizing pain perception
during GPNB in children and can be recommended as a safe, easy‐to‐use
adjunct in pediatric dental practice.}
    }