@article{MAKHILLRJMS2024181231858,
    title = {Prevalence of Subclinical Thyroid Dysfunction in Reproductive-Age Women Presenting with Abnormal Uterine Bleeding: A Cross-Sectional Study},
    journal = {Research Journal of Medical Sciences},
    volume = {18},
    number = {12},
    pages = {977-981},
    year = {2024},
    issn = {1815-9346},
    doi = {makrjms.2024.12.977.981},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2024.12.977.981},
    author = {Pranadeep and},
    keywords = {Menstrual irregularities, abnormal uterine bleeding, subclinical hypothyroidism, TSH screening subclinical hyperthyroidism, thyroid dysfunction, reproductive-age women},
    abstract = {Abnormal Uterine Bleeding (AUB) is a frequent gynecological complaint
among reproductive-age women, with multifactorial etiology. While
structural and hormonal causes are well recognized, thyroid dysfunctionparticularly
in its subclinical form is increasingly being acknowledged as
a contributing factor. Subclinical thyroid dysfunction may present without
overt symptoms yet cause significant menstrual irregularities, including
menorrhagia and oligomenorrhea. To determine the prevalence of
subclinical thyroid dysfunction in reproductive-age women presenting
with AUB and to correlate bleeding patterns with thyroid status. This
cross-sectional study was conducted in the Department of Obstetrics
and Gynecology at a tertiary care center, involving 170 women aged
18-45 years presenting with AUB. Detailed clinical evaluation and thyroid
function tests (FT3, FT4 and TSH) were performed. Based on TSH levels
with normal FT3 and FT4, patients were categorized as having subclinical
hypothyroidism or subclinical hyperthyroidism. Out of 170 women, 23
(13.5%) had subclinical hypothyroidism, while 12 (7.1%) had subclinical
hyperthyroidism. Menorrhagia was the most common bleeding
pattern among those with subclinical hypothyroidism (43.6%), whereas
oligomenorrhea was predominant in subclinical hyperthyroidism (75%).
A significant number of women with AUB were found to have underlying
thyroid dysfunction, emphasizing the importance of early screening.
Subclinical thyroid dysfunction is a common, often overlooked cause of
abnormal uterine bleeding in reproductive-age women. Routine thyroid
function screening in AUB cases can facilitate early diagnosis, appropriate
treatment and potentially prevent unnecessary surgical interventions.}
    }