@article{MAKHILLRJMS2024181231857,
    title = {Analysis of the Laboratory Profile of Liver Abscess in Patients Presenting to the Surgical Department at A Tertiary Care Centre: A Prospective Observational Study},
    journal = {Research Journal of Medical Sciences},
    volume = {18},
    number = {12},
    pages = {971-976},
    year = {2024},
    issn = {1815-9346},
    doi = {makrjms.2024.12.971.976},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2024.12.971.976},
    author = {M.,Pruthviraj,Channanna and},
    keywords = {Liver abscess, escherchia coli},
    abstract = {Liver abscess is a well‐known condition that is often caused by parasite
origin (amoebic) in underdeveloped nations and pyogenic in affluent
ones. The goal of this research was to assess the microbiological
spectrum of liver abscess, its etiological reasons, the medication
susceptibility pattern of the isolates from the liver abscess, and the illness
outcome. From January 2023 to June 2024, a prospective cross‐sectional
research was done in the Departments of General Surgery and
Microbiology among at , PES institute of medical sciences and research
at Andhra Pradesh patients diagnosed with a liver abscess in the
Department of Surgery of a tertiary care hospital. The patients were told
about the trial and given their informed permission. From January 2023
to June 2024 (18 months), 90 consecutive individuals with a liver abscess
were investigated. USG guided aspiration was used to obtain the Pus
specimen. The most common etiological aetiology of the liver abscess
(71%) was amoebic liver abscess. The most prevalent causal organism of
pyogenic liver abscess (11%) was E. coli. The bulk of the patients were
middle‐aged guys with low socioeconomic position and were chronic
drinkers. Fever (89%) and stomach discomfort (62%) were the most
prevalent symptoms, with hepatomegaly (58%) being a common
indicator. The research found complications such as abscess rupture (four
instances), sepsis (four cases), chronic liver disease (two cases), and liver
failure (two cases). The treatment approach in this research includes
beginning patients on a first empirical antibiotic regimen. In addition, in
the majority of instances, abscess drainage was performed using
fine‐needle aspiration (42%), or pigtail drainage (27%). Only 11% of the
cases were complex enough to need open surgery. Amoebic liver abscess
is the most frequent kind of liver abscess in India, followed by pyogenic
liver abscess. The most prevalent bacterium recovered from pyogenic
abscesses is E.coli. The most prevalent pattern in our investigation was a
solitary right lobe abscess. Early and adequate antibiotic therapy, as well
as abscess drainage, have resulted in a better clinical outcome.}
    }