@article{MAKHILLRJMS2024181231842,
    title = {To Evaluate the Association of Various Parameters Associated with Severity of Acute Pancreatitis‐A Prospective Observational Study},
    journal = {Research Journal of Medical Sciences},
    volume = {18},
    number = {12},
    pages = {900-904},
    year = {2024},
    issn = {1815-9346},
    doi = {makrjms.2024.12.900.904},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2024.12.900.904},
    author = {P.R.,S.,Channanna and},
    keywords = {Acute pancreatitis, abdominal pain},
    abstract = {Acute pancreatitis (AP) presents with a broad spectrum of clinical
manifestations and severity. While the majority of patients experience a
moderate course that resolves spontaneously, approximately 20% of
cases progress to a severe necrotizing form, characterized by organ
failure and mortality rates ranging from 10% to 50%. A critical component
of acute pancreatitis management is the accurate assessment of its
severity. Current scoring methods often fail to identify individuals with
severe illness, and the cost associated with generating these scores is
substantial. Consequently, this study focused on identifying individual
characteristics that may serve as early indicators of severe illness. Given
the high incidence of acute pancreatitis admissions in this region, this
topic was selected for investigation. The objective of this study was to
examine the factors associated with the severity of acute pancreatitis.
This prospective observational study aimed to evaluate the association
of clinical, biochemical, and radiological parameters with the severity of
acute pancreatitis. Conducted from August 2023 to September 2024 at
the general surgery department of the PES Institute of Medical Sciences
and Research in Andhra Pradesh, the study included eighty consecutive
patients aged 18 to 68 years who presented with symptoms of acute
pancreatitis. Diagnosis was based on clinical signs, biochemical markers,
and radiological findings. The majority of cases (37.5%) were observed in
individuals aged 40–50 years. In our study, 56 patients (70%) had mild
acute pancreatitis, 15 (18.5%) had moderately severe acute pancreatitis,
and 9 (11.25%) had severe acute pancreatitis. Alcohol consumption was
identified as the cause in 56 patients (70%), while gallstone pancreatitis
accounted for 14 cases (17.5%). Among the study population, 50 patients
(62.5%) had diabetes, 32 (40%) had hypertension, and 40 (50%) had
dyslipidemia, with diabetes mellitus being the most prevalent
comorbidity. In terms of body mass index (BMI), 38 cases (47.5%) had a
BMI between 18.5 and 24.9, 8 (10%) had a BMI over 30, and 34 (42.5%)
had a BMI between 18.5 and 19.9. Notably, 56 participants (70%)
reported a history of alcohol consumption. Effective treatment should not
rely solely on a single grading system. Diagnosis of pancreatitis should be
based on clinical, laboratory, and radiological assessments, with prompt
initiation of vigorous crystalloid resuscitation and intensive care
monitoring.}
    }