@article{MAKHILLRJMS20159631868,
    title = {Assessment of Adverse Drug Reactions in Patients Undergoing Polypharmacy in General Medicine Wards ‐ A Prospective Observational Study},
    journal = {Research Journal of Medical Sciences},
    volume = {9},
    number = {6},
    pages = {553-556},
    year = {2015},
    issn = {1815-9346},
    doi = {makrjms.2015.6.553.556},
    url = {https://makhillpublications.co/view-article.php?issn=1815-9346&doi=makrjms.2015.6.553.556},
    author = {Dr. K.N.},
    keywords = {Adverse drug reactions, polypharmacy, ADR reporting},
    abstract = {Polypharmacy, or the use of multiple medications, is a major contributor
to adverse drug reactions (ADRs). Although it carries potential risks,
combining drugs can also provide significant benefits by alleviating
symptoms, treating conditions, and preventing complications. However,
with the growing availability of over‐the‐counter drugs and alternative
medicines, maintaining a balance between the risks and benefits of
polypharmacy has become increasingly challenging. This hospital‐based
prospective observational study recorded patient data using a structured
ADR reporting form. Information collected included baseline parameters,
medical history, clinical findings, characteristics of ADRs, and details of
both the suspected medications and those used for management. Data
analysis was carried out using descriptive statistics with the Statistical
Package for the Social Sciences (SPSS) version 25.0 software. During the
study, 150 patients meeting the inclusion criteria were enrolled. Among
them, 23 developed ADRs after admission. Polypharmacy was identified
in 92 patients (61.4%), while 52 patients (38.6%) were not on
polypharmacy, showing a statistically significant difference. Polypharmacy
is a major contributor to adverse drug reactions (ADRs) due to drug–drug
interactions, inappropriate prescribing, and cumulative side effects.
Careful review of prescriptions, timely identification, and proper
management of ADRs with regular monitoring are essential. Increasing
awareness among healthcare professionals and educating patients can
help minimize preventable ADRs.}
    }