@article{MAKHILLRJAS201813710109,
    title = {Degradation of a Nonsteroidal Anti-Inflammatory Drug Using
Horseradish Peroxidase Enzyme},
    journal = {Research Journal of Applied Sciences},
    volume = {13},
    number = {7},
    pages = {425-430},
    year = {2018},
    issn = {1815-932x},
    doi = {rjasci.2018.425.430},
    url = {https://makhillpublications.co/view-article.php?issn=1815-932x&doi=rjasci.2018.425.430},
    author = {Edna and},
    keywords = {Diclofenac,enzymatic treatment,horseradish peroxidase,pharmaceutical compounds,removal efficiency,temperatures},
    abstract = {Due to the persistent feature of some compounds commonly found in wastewaters, their treatment
is very difficult through conventional processes. Therefore, alternatives among which arises the enzymatic
treatment are in continuously sought. The objective of this research is to analyze the feasibility of degradation
of a widely used pharmaceutical compound, diclofenac, using the enzyme Horseradish peroxidase as a catalyst
of the reaction. Very promising results were obtained, since, there is no evidence of the use of this enzyme for
the elimination of diclofenac compound. The influence of the initial concentration of enzyme and hydrogen
peroxide in the removal efficiency is analyzed. A maximum value of removing close to 47% was reached when
hydrogen peroxide and diclofenac were used in stoichiometric quantities. The operating conditions were also
studied. It was observed that reaction can be performed in a pH range between 6-9 and temperatures
from 20-50°C.}
    }