@article{MAKHILLRJBS20149411448,
    title = {Antibacterial and Cytotoxic Activities of Four Red Sea Soft Corals from Gulf of Aqaba-Jordan},
    journal = {Research Journal of Biological Sciences},
    volume = {9},
    number = {4},
    pages = {122-128},
    year = {2014},
    issn = {1815-8846},
    doi = {rjbsci.2014.122.128},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2014.122.128},
    author = {Wael A.},
    keywords = {Red Sea,cytotoxicity,antimicrobial,oft coral,Gulf of Aqaba,Jordan},
    abstract = {About 40% of worldwide identified soft corals are native to the Red Sea. They represent a source of compounds with potential pharmaceutical applications. Soft coral samples collected from Jordanian coast of Gulf of Aqaba were identified morphologically and anatomically and found to be <I>Sinularia polydactyla</I>, <I>S. grayi</I>, <I>S. copressa </I>and <I>Sarcophyton </I>sp. They were extracted with ethyl acetate and the resulting crude extracts were partially purified on lsilica gel column producing fractions with antimicrobial and/or cytotoxic activities. Gram positive <I>Bacillus subtilis </I>was the only inhibited test bacterial strain and Jurkat was the most affected cell line. Crude extract of <I>S. compressa </I>contains the most potent antibacterial compounds with MIC (8-62.5 &#956;g mL<SUP>-1</SUP>) and antitumor metabolites with IC (10-30 &#956;g mL<SUP>-1</SUP>). These activities are due to presence of 50 compounds with different polarities.}
    }