@article{MAKHILLRJBS20127611360,
    title = {Effect of Treatment with Negative Pressure on Wound Infection and Healing Following Open Cholecystectomy},
    journal = {Research Journal of Biological Sciences},
    volume = {7},
    number = {6},
    pages = {230-233},
    year = {2012},
    issn = {1815-8846},
    doi = {rjbsci.2012.230.233},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2012.230.233},
    author = {Mohsen Noroozi,Gholam and},
    keywords = {Cholecystectomy,surgicalwound infection,negative-pressure wound therapy},
    abstract = {Surgical wound infection after cholecystectomy is one of the 
  most common complications that increase morbidity and hospital costs. Wound 
  infection control using modern methods of wound healing can reduce these complications. 
  Negative-pressure Wound Therapy (NPWT) is a therapeutic technique using a vacuum 
  dressing to promote healing in acute or chronic wounds by which excess fluid, 
  debris and wound edema are removed. The aim of the present study is to investigate 
  the effect of NPWT on the healing rate of acute infection following cholecystectomy. 
  In this cross-sectional study, 240 patients who underwent cholecystectomy where 
  divided into two groups based on a randomized block model. Cases of surgical 
  wounds treated with NPWT and control wounds treated with classical treatment 
  methods. From 31 patients who had positive cultures from the wound site, 6.45% 
  where in case group and 93.55% where in control group (p<0.00001). Wound 
  healing rate in case group where as follows: 14 patients in grade 1, 86 patients 
  in grade 2 and 20 patients in grade 3. This rate in control group was 21, 91 
  and 8 patients for grade 1-3, respectively which was significantly different 
  (p = 0.035). NPWT may facilitate wound healing and decrease the wound infection 
  rate after cholecystectomy.}
    }