@article{MAKHILLRJBS20105311093,
    title = {<I>In vitro</I> Antifungal Activity of <I>Senna alata </I>Linn. Crude Leaf Extract},
    journal = {Research Journal of Biological Sciences},
    volume = {5},
    number = {3},
    pages = {275-284},
    year = {2010},
    issn = {1815-8846},
    doi = {rjbsci.2010.275.284},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2010.275.284},
    author = {O.G.,J.A.,J.C.,M.O.,I.O.,T.A.,O.J. and},
    keywords = {Antifungal activity,biochemical components,crude extract,dermatophytes,Phytoconstituents,Senna alata L.,MIC},
    abstract = {This study reports on the <I>in vitro </I>antifungal activity of <I>Senna alata</I> Linn. crude leaf extract on clinical test Dermatophytes. The studies on the <I>in vitro</I> investigation of antifungal activities of ethanolic extracts of <I>Senna alata </I>L. leaf was carried out. The test was conducted on Dermatophytes which included Dermatophytes of the genera <I>Trichophyton</I>,<I> Microsporum </I>and <I>Epidermophyton</I>. These fungi are the causative agents of various types of dermatophytosis which attack various parts of the body and tend to the following conditions, <I>Tinea capitis, Tinea cruris, Tinea coporis </I>and <I>Tinea pedis</I>. The results obtained showed that the leaf exudates and the ethanol extract of the leaf of <I>Senna alata </I>L. exhil: had marked antifungal effects on <I>Microsporum canis</I>,<I> Trichophyton jirrucosum</I>,<I> Trichophyton mentagrophytes</I> and <I>Epidermophyton jlorrcosum</I>. The ethanolic extract showed the highest inhibition on <I>trinchophyton verrucosuf</I> and <I>Epidermophyton jloccosum </I>with 20.50 and 20.00 mm zone of inhibition, respectively. The Minimum Inhibitory Concentration (MIC) was also performed and the result showed that the MIC of <I>Senna alata </I>L. on all the tested Dermatophytes was 5.0 mg mL<SUP>-1</SUP> which is the standard. The results obtain from the biochemical analysis of the plant <I>Senna alata </I>L. revealed the presence of Alkaloids, Saponins, Tannins, anthracionones and carbohydrates.}
    }