@article{MAKHILLRJBS20094610925,
    title = {Detection the Antibacterial Effect of Seaweeds on <I>Staphylococcus aureus</I> DNA Repair Gene (<I>adaB</I>) and Cell Wall Protein Synthesis (<I>sav1017</I>) by Molecular Approaches},
    journal = {Research Journal of Biological Sciences},
    volume = {4},
    number = {6},
    pages = {662-667},
    year = {2009},
    issn = {1815-8846},
    doi = {rjbsci.2009.662.667},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2009.662.667},
    author = {Nagi A.,Nurmas I.,Mariana N.,Habsah,Charles S. and},
    keywords = {Polymerase chain reaction,Staphylococcus aureus,seaweeds,antimicrobial activities,extraction,Malaysia},
    abstract = {Polymerase Chain reaction amplification of DNA was performed to used to study the presence and effect of treated and untreated<I> Stapylococcus aureus</I> genes<I> sav1017</I> and <I>adaB</I> with marine seaweeds <I>Gracilaria changii</I> and <I>Euchema denticulatum</I>. From the sequencing analysis, the changes were detected in the gene sequence of <I>adaB</I> and <I>sav1017</I>, genes after treated with either <I>G. changii</I> or <I>E. denticulatum</I> extract, which involved the substitution of the nucleotide base pair and insertion or deletion of the purine or pyrimidine base. The novel of this study is the extract of <I>G. changii</I> and <I>E. denticulatum</I> interrupting the important function in MRSA and non-MRSA isolates so that this pathogen cannot survive longer than usual. This significant finding can be applied to a medical treatment whereby both of these extracts can be used as an alternative treatment for the infection of <I>S. aureus</I> especially to overcome drug resistance treatment problems in MRSA strains.}
    }