@article{MAKHILLRJBS200941211030,
    title = {Antidiabetic Effect of <I>Otostegia persica</I> Oral Extract on Streptozotocin-Diabetic Rats},
    journal = {Research Journal of Biological Sciences},
    volume = {4},
    number = {12},
    pages = {1227-1229},
    year = {2009},
    issn = {1815-8846},
    doi = {rjbsci.2009.1227.1229},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2009.1227.1229},
    author = {M.R.,Z. and},
    keywords = {Antidiabetic effect,Otostegia persica,stereptozotocin,blood glucose level,rats,Iran},
    abstract = {Antidiabetic effect of the alcoholic extract of <I>Otostegia persica</I> was investigated on 40 streptozotocin diabetic rats in four equal groups. Animals in first group did not receive any extract and were as a control for other groups. Rats in group II, III and IV received 200, 350 and 500 mg kg<SUP>-1</SUP> daily administration of <I>Otostegia persica</I> oral extract, respectively for three weeks. Blood glucose level was estimated three times a day (8:00, 11:00 A.M and 5:30 P:M) in all groups. Statistical analysis of the results by t-test showed that the extract produced a dose-dependent decrease in the blood glucose level especially in fourth group (p&lt;0.0001) in comparison with first group. Thus, study indicate that <I>Otostegia persica</I> has a strong antidiabetic action and can decrease the blood glucose level.}
    }