@article{MAKHILLRJBS20083210542,
    title = {Atrial Natriuretic Factor Downregulation During Breast Cancer Progression},
    journal = {Research Journal of Biological Sciences},
    volume = {3},
    number = {2},
    pages = {246-250},
    year = {2008},
    issn = {1815-8846},
    doi = {rjbsci.2008.246.250},
    url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2008.246.250},
    author = {Biagio Valentino,Giampiero La Rocca,Rita Anzalone,Simona Corrao,Francesca Rappa,Diego Lipari,Alessandro Valentino,Giovanni Peri,Francesco Cappello and},
    keywords = {Atrial natriuretic factor,oxytocin,breast cancer,carcinogenesis},
    abstract = {We researched in a series of human breast cancers of different stages the presence and the expression of Atrial Natriuretic Factor (ANF) and Oxytocin (OX), by immunohistochemistry and RT-PCR. We found a reduction of expression of ANF during cancer progression. By contrast, OX resulted lightly expressed by immunohistochemistry and negative at RT-PCR. We hypothesize that ANF could be considered a novel marker to predict breast cancer progression; by contrast, OX expression should be better investigated, to clarify also the putative role of oxytocinases in human breast carcinogenesis.}
    }