@article{MAKHILLIJMMAS2006238574,
    title = {Dynamics of Metastasis of Breast Carcinoma to Brain},
    journal = {International Journal of Molecular Medicine and Advance Sciences},
    volume = {2},
    number = {3},
    pages = {292-298},
    year = {2006},
    issn = {1813-176x},
    doi = {ijmmas.2006.292.298},
    url = {https://makhillpublications.co/view-article.php?issn=1813-176x&doi=ijmmas.2006.292.298},
    author = {Lawrence M. Agius},
    keywords = {Dynamics,breast carcinoma,proliferation},
    abstract = {A metastatic cascade appears to operate as a non-random predetermined system of selective advantage implicating initially a sieving effect by the first capillary beds in an organ of spread.  A seed-soil predilection appears to constitute a released system of promotion enhancing progression of tumor cell proliferation as a critical step in the metastatic cascade. One might redefine events in terms of promotion of pathways influencing subsequent acquisition of attributes.  Permeation and embolic spread via vessels would constitute a realized idealization of events primarily characterized in terms of ongoing changes in phenotype of tumor cells both as genetically unstable cells and as increasingly self-progressive pathways of strictly sequential type.}
    }