@article{MAKHILLIJMMAS2006218533,
    title = {Dysfunctional Lymphocyte Turnover in Subsequent Self-Generation of Autoimmunity},
    journal = {International Journal of Molecular Medicine and Advance Sciences},
    volume = {2},
    number = {1},
    pages = {16-22},
    year = {2006},
    issn = {1813-176x},
    doi = {ijmmas.2006.16.22},
    url = {https://makhillpublications.co/view-article.php?issn=1813-176x&doi=ijmmas.2006.16.22},
    author = {Lawrence and},
    keywords = {Self genration,auoimmunity,dysfuntional,lymphocyte},
    abstract = {Reactivity responses of autoimmune origin appear a realized series of pathways in the generation of dysfunctional versus homeostatic lymphocyte turnover.  Lymphocyte responsiveness would transform to a dysfunctional state in the generation of various subsets of cells as reflected in autoimmune phenomena. It is in terms of a dysfunctionality ranging in scope from primary generation of the lymphocyte subset to subsequent creation of a whole panorama of responsive influences and pathologic lesions that autoimmunity would evolve further as a self-generated reactivity in its own right.  Indeed, oligoclonality of antibody production in the cerebrospinal fluid of multiple sclerosis patients would arise as a phenomenon both primarily generated in terms of dysfunctional lymphocyte turnover and as a secondary process in the progression of such primary autoimmune reactivity exposing native myelin epitopes.}
    }