@article{MAKHILLJAVA20212054662,
    title = {Investigation on Clinical, Haematological and Serum Biochemical Changes in Experimentally
Induced Ruminal Acidosis in Black Bengal Goats},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {20},
    number = {5},
    pages = {118-123},
    year = {2021},
    issn = {1680-5593},
    doi = {javaa.2021.118.123},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2021.118.123},
    author = {Md.,Moktadin,Mst. and},
    keywords = {Ruminal acidosis,concentrate feeding,cereals,liver enzymes,organ failures,goat},
    abstract = {Acute and chronic acidosis, conditions that
follow ingestion of excessive amounts of readily
fermented carbohydrate are prominent production
problems for ruminants fed diets rich in concentrate.
Often occurring during adaptation to concentrate-rich
diets in feedyards, chronic acidosis may continue during
the feeding period. The goal of the experiment was to
evaluate the consequences of ruminal acidosis in affected
goats. Acidosis was induced in six 12-to14-month-old
female Black Bengal goats by feeding them 90 g of rice
mixed with khesari (cereal) per kilogram of body weight.
Regular observations were made to monitor the
progression of clinical symptoms in the animals. Prior to
grain feeding (0 h), the respiration rate, heart rate and
rectal temperature were registered and blood samples
were taken at 24, 48, 72, 96 and 120 h intervals. The
respiratory rate, heart rate and rectal temperature all
increased significantly (p≤0.05) during the clinical
review. A significant (p≤0.05) increase in PCV (%),
Haemoglobin concentration, RBC values and a significant
(p≤0.05) decrease in blood pH were found in
hematological research. There was a change in WBC,
Neutrophils and Lymphocytes but it was not important.
Significantly increased activities of liver enzymes AST,
ALT and bilirubin (p≤0.05). During ruminal acidosis,
serum creatinine was found to be significantly (p≤0.05)
elevated. Triglyceride levels increased significantly
(p≤0.05) while Cholesterol levels remained unchanged,
suggesting a functional shift in the vasculature.
Lactacidemia, hepatic and renal dysfunction were found
to be the primary causes of clinical, haematological and
serum biochemical changes in acidotic Black Bengal
goats. This study discovered that ruminal acidosis has a
significant impact on vital organs such as the liver,
kidneys and circulatory system and that the owner should
take the required precautions to avoid organ failure.}
    }