@article{MAKHILLJAVA20191814568,
    title = {The Effect of Propofol and Ketamar on Both Clinical and Hematological
Parameters in Pre-Medicated Egyptian Donkeys},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {18},
    number = {1},
    pages = {5-10},
    year = {2019},
    issn = {1680-5593},
    doi = {javaa.2019.5.10},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2019.5.10},
    author = {Mohammed Zaki and},
    keywords = {General anesthesia,donkeys,blood parameter,ketamine,propofol,detomidine},
    abstract = {The present study was designed to differentiate between the effect of propofol and ketamine HCL
on both clinical and blood parameters in detomidine pre-medicated Egyptian donkeys. Six apparent healthy
donkeys were divided into two equal groups. All animals were pre-medicated by 0.2 mg/kg detomidine
intravenously, then the first Group (G1) was injected by the propofol (2 mg/kg intravenously) while the second
Group (G2) was injected by ketamine HCL (2.2 mg/kg intravenously). The onset, duration and recovery periods
were calculated for each group. Heart rate, respiratory rates and body temperatures were recorded. Blood
samples were collected at 0, 15, 30, 60 min and 6 h after the anesthetic drug injected for record any changes were
done in blood parameters. Results showed that the onset, duration and total recovery periods of anesthesia
were 6.35±3.08 and 4.52±1.23, 29.44±2.51 and 42±1.00 and 62±2.48 and 85.33±3.11 min in G1 and G2, respectively.
In G1, marked decrease in RBCs, PCV and Hb values from the zero time and presence of shallow respiration.
However, no detectable changes in blood parameters were detected in G2. In conclusion, these findings indicate
that ketamine in detomidine pre-medicated donkeys produced rapid induction, long duration, smooth induction,
recovery and sufficient anesthesia without any significant changes in all parameters. So, using of ketamine to
produce sufficient anesthesia is better in detomidine pre-medicated Egyptian donkeys in compare with the
propofol.}
    }