@article{MAKHILLJAVA20191814569,
    title = {Experimental Mastitis in Cows Induced by Field Isolates of <i>Nocardia farcinica</i>},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {18},
    number = {1},
    pages = {11-17},
    year = {2019},
    issn = {1680-5593},
    doi = {javaa.2019.11.17},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2019.11.17},
    author = {H. A. E.,Abdelbasit O.,Adil and},
    keywords = {Mastitis,cows,Nocardia farcinica,experimental infection,clinical manifestations,granulomatous},
    abstract = {Mastitis is a common disease of lactating cows and is caused by several different types of bacteria
including <i>Nocardia farcinica</i>. The objective of the current study is to demonstrate pathology clinical
manifestations of experimental mastitis in dairy cows induced by field isolates of <i>Nocardia farcinica</i>. The
infection was done by intramammary infusion in two healthy lactating dairy cows using two field isolates of
<i>N. farcinica</i>. The infected animals were examined periodically for clinical signs and laboratory profiles. The first
cow showed typical clinical signs of acute <i>Nocardia mastitis</i> with granulomatous reaction whereas the second
cow showed sub-acute clinical mastitis. While the first cow died within a few days post infection, the second
cow survived but didn&#146;t respond to standard mastitis treatment. Treatments of the experimentally induced
mastitis with Neomastipra&reg; and Gentamast&reg; failed to cure the infection and after the withdrawal period of both
drugs <i>Nocardia</i> continued to shed from udder. Clinical isolate of <i>Nocardia farcinica</i> caused mastitis that was
either subacute/irresponsive to treatment or fatal peracute leading to death.}
    }