@article{MAKHILLJAVA20151464478,
    title = {Noni Fruit Extract Induces Effective Control of Lesions in Mice Infected with <I>Leishmania amazonensis</I>},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {14},
    number = {6},
    pages = {151-154},
    year = {2015},
    issn = {1680-5593},
    doi = {javaa.2015.151.154},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2015.151.154},
    author = {Renata,Fernando,Joicy,Mylena Andrea,Fabio Henrique Evangelista,Ferdinan Almeida,Katia da Silva and},
    keywords = {Experimental infection,Morinda citrifolia,murine leishmaniasis,susceptible mice,extracellular},
    abstract = {The present study evaluated the effect of <I>Morinda citrifolia</I> crude extract on mice infected with <I>Leishmania amazonensis</I>. Both infected and untreated animals displayed severe extracellular matrix destruction, hyperplasia of the white pulp of the spleen and inflammatory cell infiltration in the liver. In contrast, animals treated with <I>M. citrifolia</I> crude extract displayedintense extracellular matrix production, characterized by the predominance of mature collagen and no alterations to the analyzed organs. The results revealed regression of lesions caused by <I>L. amazonensis</I> in the groups treated with noni extract which demonstrates that <I>M. citrifolia</I> provides effective control of the lesions caused by the infection.}
    }