@article{MAKHILLJAVA201413124359,
    title = {Characterization of Imprinted Gene Expression in Porcine Placenta},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {13},
    number = {12},
    pages = {711-718},
    year = {2014},
    issn = {1680-5593},
    doi = {javaa.2014.711.718},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2014.711.718},
    author = {Jiang,Huang,Yang and},
    keywords = {expression pattern,imprinted gene,placenta,Pig,key},
    abstract = {Imprinted genes are generally essential for the adequate development 
  and functions of the placenta in human and mice. To identify links between gene 
  imprinting and porcine placental biology, researchers characterized expression 
  of 32 candidates in Meishan and Duroc placentas on day 25, 55 and 105 of gestation 
  using real-time PCR. The results revealed 14 genes differentially expressed 
  between Meishan and Duroc placentas or over gestation stages. In Meishan placentas, 
  GO terms involving regulation of blood vessel size, organ morphogenesis, secretion 
  and cell differentiation were over-represented in the genes showing decreased 
  expression with gestation ages or higher expression than in Duroc placentas 
  at day 25 of gestation while cell cycle arrest was enriched in the genes of 
  higher levels in expression at day 105 of gestation. In contrast in Duroc placentas, 
  genes which expression decreased at late gestation were enriched in cell cycle 
  process and cell cycle arrest whereas genes which expression increased at late 
  gestation were associated with organ development and cell differentiation. Furthermore, 
  13 differential genes had marked deletion effects involving embryonic and placental 
  growth and embryonic lethality. Interestingly, transcripts of 29 imprinted genes 
  demonstrated high expression correlation, thus forming co-regulation network 
  in porcine placenta. The research indicates the essential roles and fine-tuned 
  compensatory regulation of imprinted genes in porcine placenta. It has highlighted 
  14 potential important imprinted candidates responsible for porcine placental 
  development or the regulation of placental efficiency in Meishan and Duroc breeds 
  with PEG10 being a key regulator.}
    }