@article{MAKHILLJAVA20141314171,
    title = {MicroRNAomes of Porcine Arterial and Venous Blood},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {13},
    number = {1},
    pages = {21-27},
    year = {2014},
    issn = {1680-5593},
    doi = {javaa.2014.21.27},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2014.21.27},
    author = {Lin,Lu,Jideng,Yue,Zhengjian,Xuewei and},
    keywords = {Arterial blood,miRNAs,pig,small RNA-sequencing,venous blood},
    abstract = {Blood plays an important role in many biological processes 
  and circulating microRNAs (miRNAs) in the blood have been reported to be biomarkers 
  for various physiological and pathological states. However, few studies have 
  examined porcine blood miRNAs, especially arterial blood miRNAs. Here, researchers 
  sequenced the microRNAomes of porcine arterial and venous blood samples in which 
  we identified 277 and 294 known porcine miRNAs, respectively. In both blood 
  samples, highly expressed miRNAs were implicated in erythropoiesis and angiogenesis. 
  A total of 57 miRNAs showed significantly different expression levels (p<0.01) 
  between arterial and venous blood of which seven were enriched in arterial blood 
  and five were enriched in venous blood by more than a 1.5 fold change. Interestingly, 
  functional enrichment analysis of the genes predicted to be targeted by the 
  enriched miRNAs indicated that arterial blood was mainly associated with the 
  immune response and venous blood was primarily associated with apoptosis and 
  the hypoxia response. The results suggest that the 12 miRNAs with differential 
  expression should be considered as biomarkers for physiological differences 
  between arterial and venous blood and that they may help promote the further 
  molecular diagnosis of blood.}
    }