@article{MAKHILLJAVA20131234014,
    title = {Abnormal Follicle Development in GGPPS Conditional Knockout Mice},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {12},
    number = {3},
    pages = {323-329},
    year = {2013},
    issn = {1680-5593},
    doi = {javaa.2013.323.329},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.323.329},
    author = {Honglin,ChunLei,XiuXing,Xuguang,Xueshan,Jun and},
    keywords = {ggpps,conditional knockout,follicular development,multi-oocyte follicles,IPP},
    abstract = {GGPPS is a member of prenyl transferase family catalyzing the synthesis of GGPP (Geranylgeranyl diphosphate) from Farnesyl diphosphate (FPP) and Isopentenyl diphosphate (IPP). Using cre/loxp system, researchers got oocyte specific knockout ggpps mice. Mutation of ggpps resulted in abnormality of follicular development, granulosa cell premature luteinization, theca cell hypertrophy and multi-oocyte follicles. Interaction of oocyte and granulosa cell was also changed. Oocyte-specific knockout of ggpps mice was acquired. Follicles grew abnormally in ggpps mutation mice. Interaction of oocyte and granulosa cell was also changed.}
    }