@article{MAKHILLJAVA201312234413,
    title = {Effects of Dietary Addition of β-Glucan on Pigs Infected with Salmonella Typhimuriu},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {12},
    number = {23},
    pages = {1657-1664},
    year = {2013},
    issn = {1680-5593},
    doi = {javaa.2013.1657.1664},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.1657.1664},
    author = {Won-Il,Nadeem,Byung-Dae,Amina,Bum-Seok,Ji-Hoon and},
    keywords = {β-glucan,genkwadaphnin,Aureobasidium pullan,Salmonella Typhimurium,weaned pigs},
    abstract = {Although, the antimicrobial effects of &#946;-Glucan (BG) have been described previously, the use of &#946;-glucan in food animal production has been unrealistic due to high production costs. Recently, pure &#946;-glucan could be efficiently produced by cultivating mutant <I>Aureobasidium pullans</I> which contains a disrupted <I>pul</I> gene and the new method can simplify purification process and reduce mass production costs. Thus, the effect of the &#946;-glucan purified from mutant <I>A. pullans</I> on salmonella infection in weaned pigs was evaluated in the study. Twenty, 4 weeks old pigs were randomly assigned to the following 4 groups: BG or BG-X group was provided with commercial feeds containing &#946;-glucan (10 mg kg<SUP>-1</SUP>) or containing both &#946;-glucan (10 mg kg<SUP>-1</SUP>) and Genkwadaphnin (10 mg kg<SUP>-1</SUP>), respectively; Normal Feed (NF) and Negative control (Neg.) groups were only provided with commercial feeds only. All the groups were provided with their specific diets for 2 weeks, challenged with Salmonella Typhimurium at 10<SUP>8</SUP> Colony Forming Units (CFU)/mL except for the Neg. group and sacrificed for pathological evaluation at 4 weeks after the challenge. As compared with the NF group, BG and BG-X groups showed significantly lower diarrhea incidence and salmonella shedding in feces and gained more weight after salmonella infection. Gross lesions were less severe in BG and BG-X groups but the differences reached no statistical significance. In conclusion this study demonstrated that the overall performance of weaned pigs fed &#946;-glucan derived from <I>A. pullan</I> was enhanced upon challenge with salmonella by increasing weight gains and reducing both the incidence of diarrhea and fecal shedding of salmonella.}
    }