@article{MAKHILLJAVA201312144201,
    title = {Studies on the Pharmacokinetics of Melamine in Dairy Goat},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {12},
    number = {14},
    pages = {1217-1219},
    year = {2013},
    issn = {1680-5593},
    doi = {javaa.2013.1217.1219},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.1217.1219},
    author = {Wang-Liang,Jin,Zhang and},
    keywords = {Melamine,pharmacokinetics,dairy goat,HPLC,goat},
    abstract = {This experiment was conducted to study the pharmacokinetics 
  of melamine in dairy goat. A single intravenous administration of the melamine 
  at the dose of 6.13 mg kg<SUP>-1</SUP> B.W. to 6 dairy goats. Blood samples 
  were collected at different intervals after administration and concentrations 
  of melamine were determined by HPLC Method. The plasma concentration-time data 
  of melamine was analyzed by Pharmaceutical 3P97. The results showed that two-compartment 
  open model was the optimum one of melamine in the dairy goats. The main pharmacokinetic 
  parameters were as follows: V<SUB>d</SUB> was (0.03&plusmn;0.01) L kg<SUP>-1</SUP>, 
  t<SUB>1/2&#946;</SUB> was (3.64&plusmn;0.02) h, AUC was (41.96&plusmn;0.52) 
  &#956;g h mL<SUP>-1</SUP>, Cl was (0.14&plusmn;0.01) L kg<SUP>-1</SUP> h<SUP>-1</SUP>. 
  These results indicated that the distribution of melamine in dairy goat was 
  limit and the elimination of melamine was rapid.}
    }