@article{MAKHILLJAVA201312134166,
    title = {Effects of Anionic Salts on Hypocalcaemia and Ca Homeostasis in Periparturient Dairy Cows in China},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {12},
    number = {13},
    pages = {1193-1197},
    year = {2013},
    issn = {1680-5593},
    doi = {javaa.2013.1193.1197},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.1193.1197},
    author = {Chuang,Cheng,Shi,Bo,Hong-You,Ling and},
    keywords = {Dairy cows,hypocalcaemia,DCAD,Ca homeostasis,transition period},
    abstract = {This study assessed the effect of anionic salts in the prevention 
  of hypocalcaemia in dairy cows. Fifty multiparous Holstein cows were randomly 
  divided into 5 groups: Control group (C) and 4 treatment (T1-T4) groups. The 
  T groups were fed different doses of anionic salts added to their diets from 
  day 21 pre-calving and The Dietary Cation-Anion Difference (DCAD) was 85 mEq 
  kg<SUP>-1</SUP> DM (C), -30 mEq kg<SUP>-1</SUP> DM (T1), -80 mEq kg<SUP>-1</SUP> 
  DM (T2), -130 mEq kg<SUP>-1</SUP> DM (T3) and -180 mEq kg<SUP>-1</SUP> DM (T4). 
  Plasma Ca<SUP>2+</SUP>, Hydroxyproline (HYP), 1,25-Dihydroxyvitamin D<SUB>3</SUB> 
  (DHVD), Parathyroid Hormone (PTH) and pH were determined during the transition 
  period. The results revealed that there was a relatively high incidence of hypocalcaemia 
  (80%) in the C group compared with the T groups (35-65%). Furthermore, plasma 
  concentrations of Ca<SUP>2+</SUP> and HYP in the T groups were higher than those 
  of the C group at calving (p&lt;0.05) and plasma pH value (p&lt;0.05) and PTH 
  concentration (p&lt;0.05 or p&gt;0.05) in the T groups were lower than those 
  of the C group at calving. These results suggest that anionic salts may induce 
  metabolic acidosis and reduce the incidence of hypocalcaemia. Compared to all 
  groups, cows in the T3 group had the lowest incidence of hypocalcaemia and plasma 
  PTH concentrations (p&lt;0.05) and the highest plasma Ca (p&lt;0.05) and HYP 
  (p&lt;0.05) concentrations at calving indicating that cows fed a DCAD diet of 
  -130 meq kg<SUP>-1</SUP> DM prior to calving may efficiently activate Ca homeostatic 
  mechanisms. In conclusion, anionic salts prior to calving may enhance Ca homeostasis 
  and reduce the incidence of hypocalcaemia in dairy cows.}
    }