@article{MAKHILLJAVA20121143230,
    title = {Dynamics of Cytokines Associated with IL-17 Producing Cells in Serum and Milk in Mastitis of Experimental Challenging with <I>Staphylococcus aureus</I> and <I>Escherichia coli</I> in Dairy Goats},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {4},
    pages = {475-479},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.475.479},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.475.479},
    author = {D.K.,X.Q.,Y.Q.,C.C.,Y.L.,T.T. and},
    keywords = {IL-17,mastitis inflammation,dairy goats,cytokines,China,ELISA kits},
    abstract = {Interleukin-17 is a critical pro-inflammatory cytokine in the development of autoimmunity and the immune responses against infection of bacteria, fungus and parasites. In the present study, dynamics of IL-17 and cytokines associated with IL-17 producing in serum and milk in experimental mastitis challenged with <I>S. aureus</I> and <I>E. coli</I> in dairy goats were monitored using commercial ELISA kits. The results showed that the levels of IL-17 in milk were peaked at 24 or 48 h post challenged with <I>E. coli</I> or <I>S. aureus</I>, respectively but no detectable peak was found in serum. The levels of TGF-&#946;, IL-6 and IL-1&#946; in milk were elevated in goats challenged with <I>E. coli</I> or <I>S. aureus</I> but only slight fluctuant were found in serum. These indicated that IL-17 was an important cytokine in the inflammation development of dairy goat mastitis challenged with <I>E. coli</I> or <I>S. aureus</I> and the local pro-inflammatory cytokines milieu plays an important role in the development of subclinical mastitis whether infected with <I>E. coli</I> or <I>S. aureus</I>.}
    }