@article{MAKHILLJAVA201211243890,
    title = {A Systematic Review of Endothelial Colony-Forming Cells},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {24},
    pages = {4506-4513},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.4506.4513},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.4506.4513},
    author = {Lin-Sen,Zhi-Qiang,Da-Wei,Zhao-Xia and},
    keywords = {Endothelial colony-forming cells,endothelial progenitor cells,neovascularization,hierarchy,expansion},
    abstract = {Endothelial Progenitor Cells (EPCs) may play a crucial role 
  in postnatal vasculogenesis which contribute to the development of vascular 
  biology. So far, there has not a consensus definition of EPCs. In 2004, Ingram 
  developed a single-cell clonogenic assay and identified a unique cell population 
  based on their proliferative potential in human umbilical cord blood and adult 
  peripheral blood and named this cell population as Endothelial Colony-Forming 
  Cells (ECFCs). Accumulating data suggest that ECFCs possess all the characteristics 
  of EPCs including robust clonal proliferative capacity and the ability to form 
  <I>de novo</I> blood vessels with a lumen<I> in vivo</I> and capillary-like 
  tube <I>in vitro</I>. Therefore, ECFCs may be true EPCs and have been highly 
  concerned as a superior type of cells to treat patients with vascular diseases. 
  This review will focus on the characteristics, hierarchy, expansion, functions 
  of ECFCs. Researchers attempt to provide a comprehensive understanding of the 
  cells to promote the development of cell-based therapy for patients suffering 
  from vascular diseases.}
    }