@article{MAKHILLJAVA201211223857,
    title = {Alterations in Biochemical, Hematological and Physical Parameters in Endurance Horses with Metabolic Crisis},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {22},
    pages = {4108-4114},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.4108.4114},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.4108.4114},
    author = {Lawan,Noraniza,Rasedee and},
    keywords = {Endurance horses,metabolic crisis,biochemical,hematological,physical},
    abstract = {Metabolic crisis is the complex and detrimental physiological 
  changes observed in eliminated endurance horses during endurance events. Therefore, 
  this study aims to appraise the alterations in biochemical, hematological and 
  physical parameters of endurance horses with metabolic crisis. About 174 endurance 
  horses between the ages of 6-20 years were examined to be clinically healthy 
  pre-ride and 115 were eliminated post-race as a result of metabolic crisis. 
  Blood sample was collected and physical examinations were conducted at pre and 
  post ride. The blood sample was analyzed for biochemical and hematological parameters. 
  The parameters were assessed using one-way analysis of variance. Metabolic crisis 
  leads to significant increases in heart rate (p&lt;0.0001), capillary refill 
  time (p&lt;0.005) and significant decrease in gut motility (0.006). There were 
  significant increases in RBC, Hb and PCV at (p&lt;0.0001). There were also significant 
  increases in WBC (p&lt;0.0002), band neutrophil (p&lt;0.012), segmented neutrophil 
  (p&lt;0.0001) and monocytes (p&lt;0.011). Significant decreases were seen in 
  sodium (p&lt;0.0196) and chloride (p&lt;0.0001). Significant increases were 
  also assessed in plasma protein (p&lt;0.0001), albumin (p&lt;0.0001), lactate 
  (p&lt;0.0001), creatine kinase (p&lt;0.0033), uric acid (p&lt;0.0017), gamma 
  glutamyl transferase (p&lt;0.0472), urea (p&lt;0.0014), triglyceride (p&lt;0.0041), 
  total protein (p&lt;0.0001), icterus index and bilirubin (p&lt;0.0024). Thus, 
  these changes could be indicative of metabolic crisis and poor performance in 
  endurance horses.}
    }