@article{MAKHILLJAVA201211203812,
    title = {Age-Associated Changes in Dog Synovial Membrane Fibres, Capillaries and Nerves},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {20},
    pages = {3827-3833},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.3827.3833},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.3827.3833},
    author = {Ayse Oya},
    keywords = {Dog synovial membrane,age-associated synovial changes,collagen fibres,elastic fibres,capillaries-blood vessels,nerves},
    abstract = {Age related changes in the fibres, capillaries and nerves 
  in the synovial membrane of the 24 (12 male and 12 female) Kangal hybrid-breed 
  dogs were studied. The ages of the dogs varied and were classified in 3 groups; 
  young (0-3 months), middle aged (3.5-6 months) and old (7 months to 6 years 
  old). Synovial intimal layers were made of 1-2 layered intimal cells in the 
  young group dogs and increased up from 3-5 to 2-6 multi-layered cells in the 
  middle aged and the old dogs. The subintimas of young and middle aged groups 
  were in areolar, adipose and areola-adipose types and were in fibrous type in 
  the old group dogs. The collagen fibres of young group dogs were rare and scattered 
  and they increased and occurred as bands and bundles in the synovium of the 
  middle aged and old group dogs. The collagen fibres around the capillaries were 
  rare in the young group and increased and occurred as collagen fibre bands and 
  bundles around the capillaries and large blood vessels of middle aged and old 
  group dogs. The thin elastic fibres increased from surface towards the deeper 
  parts of the subintima of young dogs. In the middle aged group dogs, elastic 
  fibres increased and thickened. The elastic fibres of the old group increased 
  more and concentrated on the walls of the blood vessels and at the peripheries 
  of the capillaries.}
    }