@article{MAKHILLJAVA201211173705,
    title = {Construction and Immunogenicity Study of a Veterinary Recombinant Influenza A (H1N1) Inactivated Vaccine},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {17},
    pages = {3213-3216},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.3213.3216},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.3213.3216},
    author = {Ming,Weixin,Wenbao,Lang and},
    keywords = {Influenza A (H1N1) virus,veterinary inactivated vaccine,recombinant,PR8 strain,immunity},
    abstract = {The recombinant virus with human H1N1 influenza virus HA, 
  <I>NA</I> gene fragments and six gene fragments of the PR8 strain was successfully 
  rescued and prepared in an recombinant (H1N1) influenza inactivated vaccine 
  as an antigen. Researchers chose BALB/c mice as animal models to evaluate the 
  vaccine&#146;s immunity. The HI test 
  results show that the vaccine can induce a high level HI antibody for human 
  influenza A virus (H1N1) and swine influenza virus (H1N1) in mice. The HI antibody 
  can be induced 1 week after immunization. Researchers monitored for 8 weeks 
  after the second immunization and high antibody levels remained. The mouse challenge 
  protection test showed that the vaccine can effectively protect the attack of 
  the human influenza A (H1N1) and swine influenza virus (H1N1). It provides technical 
  reserves for preventing a pandemic H1N1 influenza in the future in swine or 
  other mammals.}
    }