@article{MAKHILLJAVA20121193390,
    title = {Association of Single Nucleotide Polymorphism in Pancreatic Lipase Gene with Growth-Related Traits in Japanese Black Beef Cattle},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {9},
    pages = {1346-1349},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.1346.1349},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.1346.1349},
    author = {Takahisa Yamada,Hideki,Youji Muramatsu,Takuji Yamamoto,Takeshi Ohta and},
    keywords = {Association,beef cattle,growth-related trait,Japanese Black breed,single nucleotide polymorphism,PNLIP},
    abstract = {Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. Researchers have recently reported that a Single Nucleotide Polymorphism (SNP) referred to as rs41648172 in intron 6 region of the Pancreatic Lipase (<I>PNLIP</I>) gene was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. The PNLIP is known to be involved in the hydrolysis of dietary triglycerides to fatty acids which is essential for the intestinal absorption of long-chain triglyceride fatty acids. Thus, the PNLIP was considered as a functional candidate for the gene responsible for growth performance. In this study, researchers analyzed the effect of the PNLIP rs41648172 SNP genotypes on the growth-related traits in Japanese Black beef cattle. The SNP was associated with carcass weight, rib eye area, rib thickness and daily gain in the experiment using 367 paternal half-sib progeny steers from a sire homozygous for C allele at the rs41648172 in Japanese Black beef cattle. The SNP was also associated with carcass weight, rib eye area and daily gain in the experiment using 587 paternal half-sib progeny steers from a sire homozygous for T allele at the rs41648172 in Japanese Black beef cattle. These findings suggest possible effect of the rs41648172 on the growth-related traits in Japanese Black beef cattle. The PNLIP SNP polymorphism may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.}
    }